When belly fat went down in these patients, their trunk muscles also got less fatty—suggesting the same process might be cleaning up both types of fat.

For HIV patients with belly fat on tesamorelin, losing belly fat was linked to better muscle density in their abdominal and rectus muscles.

For HIV patients with belly fat who responded to this drug, taking tesamorelin for 6 months made their trunk muscles less fatty and more dense, like turning soft muscle into firmer muscle.

For people with HIV and belly fat who responded to tesamorelin by losing belly fat, taking the drug for 26 weeks made their trunk muscles denser by 1.56 to 4.86 units compared to those who didn't take it.

This drug only helped people whose belly fat went down a lot—so if your belly fat didn’t shrink, we don’t know if it would help your muscles.

This drug didn’t just make muscles less fatty—it also made them bigger in size, adding about half a square inch of lean muscle in the core area after six months.