In cow liver cells, a substance called acetate boosts a protein that helps burn fat, and the more acetate you add, the stronger the effect — but this only happens when another key energy-sensing switch is turned on.

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Pro

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Evidence from Studies

Supporting (1)

11

Community contributions welcome

11

Acetic Acid Activates the AMP-Activated Protein Kinase Signaling Pathway to Regulate Lipid Metabolism in Bovine Hepatocytes

Cross-Sectional Study

Animal

2013

The study shows that acetate increases the activity of a fat-burning switch in cow liver cells, and this effect depends on another energy-sensing switch called AMPK. When researchers blocked that sensor, the effect went away.

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No contradicting evidence found

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Source Study

Acetic Acid Activates the AMP-Activated Protein Kinase Signaling Pathway to Regulate Lipid Metabolism in Bovine Hepatocytes

Score: 11

DOI: 10.1371/journal.pone.0067880

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