When delivered through the nose, stem cell vesicles reach and are absorbed by microglia and astrocytes in the brains of aged mice, indicating they can specifically target brain immune and support...

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Evidence from Studies

Supporting (1)

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Intranasal Human NSC‐Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS‐STING Signalling, in Aged Hippocampus

Cohort Study

Animal & In Vitro

2026 Feb

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Source Study

Intranasal Human NSC‐Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS‐STING Signalling, in Aged Hippocampus

Score: 13

DOI: 10.1002/jev2.70232