The Claim
Whole-body insulin action, measured by in vivo insulin tolerance, is progressively reduced in obese men compared to normal-weight control subjects, with the magnitude of reduction being most pronounced in individuals presenting with combined obesity, hyperinsulinemia, and glucose intolerance.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Doctors have found that when men carry extra weight, their bodies become less good at responding to insulin - and this gets worse the more weight-related health problems they have.
See the scientific wording
In vivo insulin tolerance (whole-body insulin action) is progressively reduced in obese men compared to normal-weight controls, with the reduction being greatest in those with combined obesity, hyperinsulinemia, and glucose intolerance
What the research says
1 studyThe study directly measured insulin action in obese men with different combinations of metabolic problems and found that insulin tolerance gets progressively worse going from normal weight to obese, then to obese with high insulin, and worst of all in obese people with high insulin and glucose intolerance - exactly matching what the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.