correlational
Analysis v1
Strong Support
Doctors have found that when men carry extra weight, their bodies become less good at responding to insulin - and this gets worse the more weight-related health problems they have.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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The study directly measured insulin action in obese men with different combinations of metabolic problems and found that insulin tolerance gets progressively worse going from normal weight to obese, then to obese with high insulin, and worst of all in obese people with high insulin and glucose intolerance - exactly matching what the claim says.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.