The Claim
In overnight-fasted healthy adults, elevated circulating free fatty acids from 0.73 to 1.53 mmol/L under low insulin conditions (~13 μU/ml) more than double hepatic ketone body production from 3.6 to 8.2 μmol·kg⁻¹·min⁻¹.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When healthy adults haven't eaten overnight and have low insulin levels, having higher levels of fatty acids in their blood (about double the normal amount) makes their liver produce more than twice as many ketone bodies - the molecules your body makes when breaking down fat for energy.
See the scientific wording
Elevated free fatty acids from 0.73 to 1.53 mmol/l during low insulin conditions (~13 μU/ml) more than double hepatic ketone body production from 3.6 to 8.2 μmol·kg⁻¹·min⁻¹ in overnight-fasted healthy adults
What the research says
1 studyStudy: Fatty acid-independent inhibition of hepatic ketone body production by insulin in humans.
The study gave people extra fats (through an IV) to raise their blood fat levels while keeping insulin low, then measured how much ketone their livers produced. The results matched exactly what the claim said - raising fats from 0.73 to 1.53 mmol/L more than doubled ketone production from 3.6 to 8.2 units.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.