mechanistic
Analysis v1
Strong Support
In human fat cells grown in the lab, long-chain fatty acids at a specific concentration reduce the ability of certain receptors to block fat breakdown, which may explain how dietary fat promotes fat utilization at the cellular level.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Acute exposure to long-chain fatty acids impairs α2-adrenergic receptor-mediated antilipolysis in human adipose tissue Published, JLR Papers in Press, July 11, 2007.
Randomized Controlled Trial
Human & In Vitro
2007 OctWhen fat levels in the blood rise after eating fatty food, fat cells stop listening to the signal that normally tells them to hold onto fat. This lets them break down fat more easily, even without other hormones involved.
Contradicting (0)
0
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No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.