correlational
Strong Support
When fat tissue around the heart and blood vessels was soaked in a blue dye called methylene blue for a day in the lab, it made less of a harmful enzyme and produced fewer damaging chemicals, which might help explain how the dye could protect cells.
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Evidence from Studies
Supporting (1)
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Methylene blue reduces monoamine oxidase expression and oxidative stress in human cardiovascular adipose tissue
Cross-Sectional Study
Human
2025 AprScientists found that adding a small amount of methylene blue to fat tissue around the heart and blood vessels lowered a harmful enzyme (MAO-A) and reduced damaging chemicals called free radicals, suggesting methylene blue can help calm oxidative stress in these tissues.
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No contradicting evidence found