mechanistic
Analysis v1
Strong Support
Eating dinner later than usual, relative to a person's internal body clock, raises blood glucose but does not significantly change insulin levels after the meal. This suggests that the body's insulin response becomes less tightly linked to glucose changes under circadian misalignment.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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0007 Comparing Post-prandial Glycemia After Late Eating vs Late Sleep: Preliminary Results from a Randomized Crossover Study
Randomized Controlled Trial
Human
When people eat late at night—especially when it’s out of sync with their body’s internal clock—their blood sugar goes up more than usual, but their body doesn’t make more insulin to fix it. This suggests their body isn’t responding to insulin as well, even if they’re healthy.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.