If young men eat a lot of phosphate for five days, their bodies start peeing out less calcium—probably because the phosphate and calcium stick together in the gut before they can be absorbed.

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Pro

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Against

Evidence from Studies

Supporting (1)

54

Community contributions welcome

54

Controlled dietary phosphate loading in healthy young men elevates plasma phosphate and FGF23 levels

Randomized Controlled Trial

Human

2025 Mar

The study gave young men more phosphate in their diet for 5 days and found they peed out less calcium — just like the claim said. So yes, more phosphate seems to help the body hold onto calcium.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Controlled dietary phosphate loading in healthy young men elevates plasma phosphate and FGF23 levels

Score: 54

DOI: 10.1007/s00424-024-03046-4

Similar Assertions

If healthy young men eat more phosphate-rich food for just five days, their blood phosphate levels go up—and so does a hormone called iFGF23 that helps control phosphate in the body.

54

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78%

When healthy young men eat a lot of phosphate for five days, their body doesn’t change the levels of several key hormones — so scientists think a different hormone called FGF23 is the main one responding to the extra phosphate.

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75%

If young men eat a lot of phosphate for five days, their body makes less of a special hormone called Klotho that helps keep bones and kidneys healthy — so too much phosphate might quiet down this helpful hormone.

54

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75%