If you've had a heart transplant and start taking a PCSK9 inhibitor for cholesterol, it probably won't mess with your anti-rejection medication levels.

Pro

Against

Evidence from Studies

Supporting (1)

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PCSK9 inhibitors safely and effectively lower LDL after heart transplantation: a systematic review and meta-analysis

Systematic Review With Meta-Analysis

Human

2023 Jan

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

PCSK9 inhibitors safely and effectively lower LDL after heart transplantation: a systematic review and meta-analysis

Score: 41

DOI: 10.1007/s10741-022-10255-5

Similar Assertions

People who got a new heart and took a drug called a PCSK9 inhibitor didn’t have serious side effects from the medicine — in fact, none of the 97 patients studied had problems caused by the drug over nearly two years.

80%

Heart transplant patients taking PCSK9 inhibitor drugs don’t seem to develop harmful immune reactions to their new heart in the first month, which means their body isn’t showing early signs of rejecting it.

77%

For some people who've had a heart transplant, taking PCSK9 inhibitor drugs might help keep the inside of their heart's blood vessels from getting narrower over time.

71%

For people who've had a heart transplant and can't take cholesterol pills like statins, a newer medicine called a PCSK9 inhibitor might help lower their bad cholesterol by about 83 points over a year.

70%