The Claim
Selenite supplementation at 100 nM increases glutathione peroxidase activity in human colon carcinoma (HT29) and mesothelioma (P31) cells, which reduces hydrogen peroxide-induced DNA single-strand breaks, but does not improve cell survival following hydrogen peroxide exposure, indicating that reduction in DNA damage does not necessarily result in enhanced cellular viability under oxidative stress.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In laboratory-grown human cancer cells, adding a small amount of selenite boosts an enzyme that reduces DNA damage caused by hydrogen peroxide, but this does not help the cells survive the stress.
See the scientific wording
Increasing glutathione peroxidase activity in human colon carcinoma (HT29) and mesothelioma (P31) cells via 100 nM selenite supplementation reduces hydrogen peroxide-induced DNA single-strand breaks, but does not improve cell survival following peroxide exposure, indicating that DNA damage reduction does not necessarily translate to enhanced cellular viability under oxidative stress.
What the research says
1 studyAdding a small amount of selenium made cancer cells better at repairing DNA damage caused by hydrogen peroxide, but it didn’t help the cells survive longer — showing that fixing DNA doesn’t always mean the cell stays alive.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.