Being exposed to a certain chemical (SCCPs) at a specific level seems to mess up how liver cells burn fat, based on lab tests with human liver cells in a dish.

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Evidence from Studies

Supporting (1)

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Exposure to short-chain chlorinated paraffins inhibited PPARα-mediated fatty acid oxidation and stimulated aerobic glycolysis in vitro in human cells.

Cross-Sectional Study

In Vitro

2021 Jun 10

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Exposure to short-chain chlorinated paraffins inhibited PPARα-mediated fatty acid oxidation and stimulated aerobic glycolysis in vitro in human cells.

Score: 3

DOI: 10.1016/j.scitotenv.2021.144957

Similar Assertions

When liver cells are exposed to a common pollutant at a certain level, they start changing how they make energy — switching from their normal method to one usually seen in cancer cells, even though they're not cancerous.

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