correlational
Analysis v1
Strong Support
When people follow identical strict diet and exercise regimens with a 1000 kcal daily deficit, they lose different amounts of weight—between 1 and 8 kg over 100 days—and identical twins tend to lose similar amounts, indicating that genetics may influence how the body responds to calorie restriction.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
1
About Unsuccessful Responders to Diet and Physical Activity Interventions: A Focus on Energy Balance and Body-Weight Loss
Narrative Review
Human
2026 Jan 7Even when people follow diet and exercise plans exactly, some lose a lot of weight and others lose little or even gain weight—and this seems to be partly because of their genes.
Contradicting (0)
0
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No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.