The Claim
Elevated plasma insulin at high physiological concentrations (~110 μU/ml) substantially restrains hepatic ketone body production induced by elevated free fatty acids, reducing production from 8.2 to 3.8 μmol·kg⁻¹·min⁻¹ in healthy adults.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When insulin levels get really high in the blood (around 110 units), it strongly stops the liver from making ketone bodies (which the body makes when breaking down fats), cutting the production rate by more than half in healthy people.
See the scientific wording
Elevated plasma insulin to high physiological concentrations (~110 μU/ml) substantially restrains hepatic ketone body production induced by elevated free fatty acids, reducing production from 8.2 to 3.8 μmol·kg⁻¹·min⁻¹ in healthy adults
What the research says
1 studyStudy: Fatty acid-independent inhibition of hepatic ketone body production by insulin in humans.
The study gave people extra fat (Intralipid) to raise their fatty acid levels, then measured how much ketone bodies their livers produced. When insulin was kept low, ketone production went up to 8.2. When insulin was raised to about 110 microU/ml, ketone production dropped to only 3.8 - exactly matching what the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.