When it's cold outside, your body makes more PGC-1alpha protein, which helps you generate heat to stay warm
Scientific Claim
Cold exposure strongly induces PGC-1alpha expression, linking environmental temperature to adaptive thermogenesis
Original Statement
“It is strongly induced by cold exposure, linking this environmental stimulus to adaptive thermogenesis.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
This is a well-established physiological response that has been demonstrated in multiple studies. The study correctly states this relationship without implying causation beyond what is known.
More Accurate Statement
“Cold exposure strongly induces PGC-1alpha expression, linking this environmental stimulus to adaptive thermogenesis”
Evidence from Studies
Supporting (1)
PGC-1alpha: a key regulator of energy metabolism