mechanistic
Analysis v1
Strong Support
When healthy adult men are in a state of severe calorie deficit at high altitude, consuming 2.0 grams of protein per kilogram of body weight per day leads to a higher rate of protein breakdown compared to consuming 1.0 gram per kilogram, resulting in a greater overall loss of body protein.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Severe negative energy balance during 21 d at high altitude decreases fat‐free mass regardless of dietary protein intake: a randomized controlled trial
Randomized Controlled Trial
Human
2018 FebIn men at high altitude who weren’t eating enough calories, eating more protein made their bodies burn more protein for energy and left them with even less protein overall—exactly what the claim says. It didn’t help them keep muscle, but that’s not what the claim was about.
Contradicting (0)
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Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.