mechanistic
Analysis v1
Strong Support

When healthy adult men are in a state of severe calorie deficit at high altitude, consuming 2.0 grams of protein per kilogram of body weight per day leads to a higher rate of protein breakdown compared to consuming 1.0 gram per kilogram, resulting in a greater overall loss of body protein.

46
Pro
0
Against

Evidence from Studies

Supporting (1)

46

Community contributions welcome

In men at high altitude who weren’t eating enough calories, eating more protein made their bodies burn more protein for energy and left them with even less protein overall—exactly what the claim says. It didn’t help them keep muscle, but that’s not what the claim was about.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.