Analysis Version
v1
History
Back to Study: B-Cell Receptor-Associated Protein 31 Deficiency A...
quantitative
Analysis v1
Strong Support

When mice lack BAP31 and drink alcohol, their liver cells leak more enzymes into the blood, showing they’re more damaged.

12
Pro
0
Against

Evidence from Studies

Supporting (1)

12

Community contributions welcome

12

B-Cell Receptor-Associated Protein 31 Deficiency Aggravates Ethanol-Induced Liver Steatosis and Liver Injury via Attenuating Fatty Acid Oxidation and Glycogen Synthesis

Cohort Study
Animal
2025 Dec 18

Scientists removed a protein called BAP31 from mice and gave them alcohol. The mice without BAP31 had much higher levels of liver damage markers than normal mice, proving that lacking this protein makes alcohol hurt the liver more.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

B-Cell Receptor-Associated Protein 31 Deficiency Aggravates Ethanol-Induced Liver Steatosis and Liver Injury via Attenuating Fatty Acid Oxidation and Glycogen Synthesis

Score: 12
DOI: 10.3390/ijms262412173

Similar Assertions

When mice don’t have the BAP31 protein and drink alcohol, their livers can’t fight off damaging free radicals as well, leading to more cell damage and signs of injury.

12
0
84%

When mice lack a specific liver protein called BAP31 and drink alcohol, their livers store way more fat because they can't burn it off properly, making fatty liver disease worse.

12
0
81%

When mice lack BAP31 and drink alcohol, their livers can’t store sugar properly, leading to low blood sugar and less energy for the body.

12
0
80%

When mice don’t have BAP31 and drink alcohol, their liver cells get overwhelmed with misfolded proteins, triggering a stress response that damages the cells.

12
0
75%