Claim
causal
When middle-aged pet dogs got rapamycin for 10 weeks, their hearts worked better - both the squeezing and relaxing phases improved.
Evidence from Studies
No evidence studies found yet.
What Would Prove This
Per GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this claim, ordered from strongest to weakest.
1
Randomized Controlled Trials
Establish whether rapamycin improves cardiac function in elderly humans
Double-blind RCT of 200 adults aged 70+ with age-related cardiac dysfunction, randomized to rapamycin vs placebo for 6 months, with cardiac MRI as primary endpoint