The Claim
Triiodothyronine (T3) increases steady-state StAR mRNA levels by approximately 3.6-fold and progesterone production by approximately 4.0-fold in mouse Leydig tumor cells, indicating a coordinated upregulation of steroidogenic gene expression and hormone output.
What the research says
Roughly balanced
Support and challenge are close. The picture may shift as more studies come in.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
A hormone called T3 makes certain mouse cancer cells produce more of a key protein and more of the hormone progesterone, as if it’s turning up the volume on both the recipe and the final product.
See the scientific wording
Triiodothyronine (T3) increases steady-state StAR mRNA levels by approximately 3.6-fold and progesterone production by approximately 4.0-fold in mouse Leydig tumor cells, indicating a coordinated upregulation of steroidogenic gene expression and hormone output.
What the research says
1 studyStudy: Molecular Mechanisms of Thyroid Hormone-stimulated Steroidogenesis in Mouse Leydig Tumor Cells
The study gave mouse cancer cells a thyroid hormone called T3 and found that it made them produce 3.6 times more of a key gene (StAR) and 4 times more progesterone — exactly what the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.