The Claim
In human primary myoblasts derived from healthy young adults, treatment with 1 nmol/L of 1,25-dihydroxyvitamin D3 for 18 hours is associated with a 36% increase in vitamin D receptor (VDR) mRNA expression compared to untreated controls, suggesting a direct regulatory effect of active vitamin D on VDR gene expression in human muscle precursor cells.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When scientists gave a specific form of vitamin D to muscle cells from young, healthy people for 18 hours, they noticed the cells made 36% more of a protein that helps vitamin D work — suggesting vitamin D might tell these cells to make more of this protein themselves.
See the scientific wording
In human primary myoblasts derived from healthy young adults, treatment with 1 nmol/L of 1,25-dihydroxyvitamin D3 for 18 hours is associated with a 36% increase in vitamin D receptor (VDR) mRNA expression compared to untreated controls, suggesting a direct regulatory effect of active vitamin D on VDR gene expression in human muscle precursor cells.
What the research says
1 studyScientists gave human muscle precursor cells a small amount of active vitamin D for 18 hours and found the cells made 36% more of the vitamin D receptor protein, just like the claim said.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
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