correlational
Analysis v1
Strong Support
When guys who lift weights gain muscle, their muscle cells also hold more water — and this happens whether or not they take creatine. It suggests that growing muscle might be linked to how much water the cells hold.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
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Creatine Supplementation Does Not Influence the Ratio Between Intracellular Water and Skeletal Muscle Mass in Resistance-Trained Men.
Randomized Controlled Trial
Human
2020 Nov 1The study found that when muscle mass went up, so did the amount of water inside the muscle cells, which supports the idea that muscle growth is linked to cell hydration.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.