When you exercise, your muscles need to take in sugar from your blood. This happens through a series of chemical signals that act like a relay race - some signals start the process near the muscle surface, and others finish the job inside the muscle cells.

The study confirms that when muscles contract during exercise, they take up glucose through specific signaling pathways - exactly as described in the claim. It verifies that AMPK, Ca2+, and NOS start the signal in the proximal part, while GTPases, Rab, SNARE proteins, and cytoskeletal components complete it in the distal part.