The Claim

In obese adults, yellow fever immunization induces measurable changes in insulin, glucagon, lactate, and ketone bodies, and these metabolic changes are modulated by the ingestion of 100 grams of glucose alongside protein.

Source: Effect of diet on the metabolic response to infection: protein-sparing modified fast plus 100 grams glucose and yellow fever immunization.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
37score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

In obese adults, receiving the yellow fever vaccine causes measurable changes in insulin, glucagon, lactate, and ketone bodies, and these changes differ when 100 grams of glucose are consumed with protein compared to when they are not.

See the scientific wording

In obese adults, the metabolic response to yellow fever immunization includes measurable changes in insulin, glucagon, lactate, and ketone bodies, and these changes are influenced by whether the diet includes 100 grams of glucose alongside protein.

Why this might work

When a person eats 100 grams of glucose with protein, their pancreas releases insulin, which stops the body from breaking down fat and making ketones. During infection, the liver needs to release more sugar into the blood, and insulin’s presence makes the body rely on glucagon to keep that process going. Without glucose, the body breaks down fat for energy, making ketones and raising glucagon naturally, but adding glucose changes this balance and forces the liver to respond differently to infection.

Supported mechanismbased on 1 study

What the research says

1 study

  1. Study: Effect of diet on the metabolic response to infection: protein-sparing modified fast plus 100 grams glucose and yellow fever immunization.

    When obese people got a yellow fever vaccine, their blood sugar hormones and energy molecules changed differently depending on whether they ate sugar with their protein. Adding sugar made glucagon go up, but without sugar, insulin and lactate rose and ketones fell—exactly as the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.