When it comes to storing fat, insulin works the same way in obese men and women — but where they differ is in how well their bodies can break down fat, not how well they store it.

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Pro

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Against

Evidence from Studies

Supporting (1)

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Community contributions welcome

49

Sex differences in adipose insulin resistance are linked to obesity, lipolysis and insulin receptor substrate 1

Cross-Sectional Study

Human

2024 Jul

In obese people, insulin works the same way in men and women to store fat, but it's worse at stopping fat breakdown in men — so the problem is with fat release, not fat storage.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Sex differences in adipose insulin resistance are linked to obesity, lipolysis and insulin receptor substrate 1

Score: 49

DOI: 10.1038/s41366-024-01501-x

Similar Assertions

When people are obese, men’s fat tissue is less responsive to insulin than women’s, meaning their bodies have a harder time using insulin to manage fat storage — and this difference is very clear in studies.

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