In older adults who are healthy, giving them thyroid hormones (either through a shot or a pill) can make a key growth-related protein called IGF-1 go up by 6–9% in just one day — and this might happen even if their growth hormone levels don’t change.

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Evidence from Studies

Supporting (1)

40

Community contributions welcome

40

Effect of Thyroid Status Modulation on Pituitary and Peripheral Hormone Concentrations in Healthy Older Subjects

Cross-Sectional Study

Human

2025

Scientists gave older adults either a TSH shot or T3 pills and found their IGF-1 levels went up by about 6–9% in a day or two — just like the claim said — without changing growth hormone, meaning thyroid hormones can boost IGF-1 on their own.

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No contradicting evidence found

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Source Study

Effect of Thyroid Status Modulation on Pituitary and Peripheral Hormone Concentrations in Healthy Older Subjects

Score: 40

DOI: 10.1159/000542832

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72%