When older adults without thyroid problems are given hormones that boost thyroid activity, their stress hormone (cortisol) drops by about 12–16% over a couple of days, which suggests that the thyroid and stress systems talk to each other.

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Pro

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Against

Evidence from Studies

Supporting (1)

40

Community contributions welcome

40

Effect of Thyroid Status Modulation on Pituitary and Peripheral Hormone Concentrations in Healthy Older Subjects

Cross-Sectional Study

Human

2025

The study gave older adults thyroid hormones and found their stress hormone (cortisol) went down by about 15%, just like the claim said it would. So yes, the study supports the idea that thyroid and stress hormones talk to each other.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Effect of Thyroid Status Modulation on Pituitary and Peripheral Hormone Concentrations in Healthy Older Subjects

Score: 40

DOI: 10.1159/000542832

Similar Assertions

When older adults get more thyroid hormone—either through a shot or a pill—their prolactin levels drop by about 8–12% in just a couple of days, and this drop is bigger in men, suggesting thyroid hormone naturally lowers prolactin no matter how you give it or whether you're male or female.

40

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76%

In older adults who are healthy, giving them thyroid hormones (either through a shot or a pill) can make a key growth-related protein called IGF-1 go up by 6–9% in just one day — and this might happen even if their growth hormone levels don’t change.

40

0

75%