mechanistic
Analysis v1
Strong Support
When older people do strength training for four weeks, those who get much bigger muscles also see a big jump in the cellular machinery that helps build muscle, while people who don’t gain muscle don’t see this change—so it seems like making more of this machinery is tied to getting stronger and bigger.
46
0
Evidence from Studies
Supporting (1)
46
Community contributions welcome
46
In older adults who did weight training for 4 weeks, those who got much stronger and bigger muscles also made more ribosomes — the cell’s protein factories — while those who didn’t grow didn’t make more ribosomes. This suggests ribosomes help muscles grow bigger.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.