The Claim

In older adults diagnosed with acute ischemic stroke, oral supplementation with 20 grams per day of creatine for 7 days leads to increased serum creatinine levels, indicating enhanced creatine metabolism and confirming systemic bioavailability of the administered supplement.

Source: Influence of CReatine Supplementation on mUScle Mass and Strength After Stroke (ICaRUS Stroke Trial): A Randomized Controlled Trial

What the research says

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Supports
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Challenges
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These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
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In plain English

If older adults who've had a certain kind of stroke take 20 grams of creatine every day for a week, their body shows signs that it's absorbing and using the supplement, based on a rise in a related blood marker.

See the scientific wording

In older adults with acute ischemic stroke, 20 g/day of oral creatine supplementation for 7 days increases serum creatinine levels, reflecting increased creatine metabolism and confirming systemic bioavailability of the supplement.

Score breakdown, mechanism chain, raw evidence, ideal studies needed

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