The Claim

In older, mobility-limited women with vitamin D insufficiency, the increase in intramyonuclear vitamin D receptor concentration is strongly correlated with the rise in serum 25-hydroxyvitamin D levels, independent of treatment group, suggesting a direct biological link between vitamin D status and muscle receptor expression.

Source: A randomized study on the effect of vitamin D₃ supplementation on skeletal muscle morphology and vitamin D receptor concentration in older women.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
61score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

When older women who have trouble moving around get more vitamin D in their blood, their muscle cells seem to respond by making more vitamin D receptors — and this happens no matter how they got the vitamin D, like from pills or sun exposure.

See the scientific wording

In older, mobility-limited women with vitamin D insufficiency, the increase in intramyonuclear vitamin D receptor concentration is strongly correlated with the rise in serum 25-hydroxyvitamin D levels, independent of treatment group, suggesting a direct biological link between vitamin D status and muscle receptor expression.

What the research says

1 study
  1. Study: A randomized study on the effect of vitamin D₃ supplementation on skeletal muscle morphology and vitamin D receptor concentration in older women.

    The study gave older women vitamin D pills and found that when their blood vitamin D levels went up, so did the number of vitamin D receptors in their muscle cells — even if they didn’t take the pills — showing a real connection between vitamin D in the blood and muscle changes.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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