The Claim
The cessation of pain induces the release of dopamine and endogenous opioids, which function as substitute reward signals in individuals with anhedonia and diminished natural reward pathway activity.
What the research says
Not yet evaluated
We are still looking at what the research says.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When pain stops, the brain releases dopamine and natural opioid chemicals that activate reward pathways, replacing the reduced reward response seen in people with anhedonia.
See the scientific wording
The cessation of pain triggers a neurochemical response involving dopamine and endogenous opioid release, which may serve as a substitute reward for individuals with anhedonia whose natural reward pathways are blunted.
When pain stops, the body releases natural painkillers and dopamine chemicals that activate the brain's reward center, giving a strong feeling of relief or calm. This happens because the reward center is normally quiet in people who can't feel pleasure from everyday things, so the sudden surge from pain ending becomes the only way to feel something positive.
What the research says
1 studyPeople who feel emotionally numb sometimes hurt themselves not to escape pain, but because the intense feeling helps their brain wake up and feel something—even if it’s not happiness. This study suggests that’s because their normal pleasure system is broken, and strong sensations might trigger the brain’s reward chemicals.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.