The Claim

Aspartame is hydrolyzed in humans and multiple animal species to release methanol, which is subsequently oxidized to carbon dioxide via the one-carbon metabolic pool, and the resulting dipeptide is cleaved by intestinal dipeptidases to release free aspartic acid and phenylalanine, which are then absorbed.

Source: Comparative metabolism of aspartame in experimental animals and humans.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
20score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

When you eat or drink something with aspartame, your body breaks it down into smaller pieces, including methanol (which turns into carbon dioxide), and two amino acids—aspatic acid and phenylalanine—that your body absorbs.

See the scientific wording

Aspartame is hydrolyzed in humans and multiple animal species to release methanol, which is oxidized to carbon dioxide via the one-carbon metabolic pool, and the resulting dipeptide is cleaved by intestinal dipeptidases to release free aspartic acid and phenylalanine, which are absorbed.

What the research says

1 study
  1. Study: Comparative metabolism of aspartame in experimental animals and humans.

    The study showed that when people and animals eat aspartame, their bodies break it down exactly as the claim says — into methanol, aspartic acid, and phenylalanine, which are then used or expelled in predictable ways.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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