When people are seriously ill but their thyroid gland is functioning normally, their bodies convert less of the inactive thyroid hormone (T4) into the active form (T3) in tissues outside the thyroid....

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Evidence from Studies

Supporting (1)

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Peripheral metabolism of thyroid hormones in man. I. Direct measurement of the conversion rate of thyroxine to 3,5,3'-triiodothyronine (T3) and determination of the peripheral and thyroidal production of T3.

Cross-Sectional Study

Human

1983 Jun

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No contradicting evidence found

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Source Study

Peripheral metabolism of thyroid hormones in man. I. Direct measurement of the conversion rate of thyroxine to 3,5,3'-triiodothyronine (T3) and determination of the peripheral and thyroidal production of T3.

Score: 47

DOI: 10.1210/JCEM-56-6-1152