correlational
Analysis v1
Strong Support
When people eat or drink things with aspartame (like diet soda), their blood phenylalanine goes up — and this happens more if they haven’t eaten recently, even if they don’t have the genetic condition PKU.
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Evidence from Studies
Supporting (1)
1
Community contributions welcome
1
Aspartame Metabolism in Normal Adults, Phenylketonuric Heterozygotes, and Diabetic Subjects
Narrative Review
Human
1989 JanThis study looked at what happens to a chemical called phenylalanine in people’s blood after they eat or drink aspartame, and it found that it goes up — just like the claim says. It also checked this in different situations, like when people are fed or fasting, which matches the claim too.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.