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Analysis v1
Strong Support

When people with low growth hormone fast for a day and a half, giving them their hormone medicine helps their bodies keep building and keeping proteins instead of breaking them down.

37
Pro
0
Against

Evidence from Studies

Supporting (1)

37

Community contributions welcome

37

Continuation of Growth Hormone (GH) Substitution during Fasting in GH-Deficient Patients Decreases Urea Excretion and Conserves Protein Synthesis<sup>1</sup>

Randomized Controlled Trial
Human
2001 Jul

When people with low growth hormone fast for 40 hours, giving them their usual hormone shot helps their bodies keep building proteins instead of breaking them down — and the study proved it by measuring protein-making activity.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Continuation of Growth Hormone (GH) Substitution during Fasting in GH-Deficient Patients Decreases Urea Excretion and Conserves Protein Synthesis<sup>1</sup>

Score: 37
DOI: 10.1210/JCEM.86.7.7618

Similar Assertions

When people with low growth hormone take their hormone while fasting, their bodies make less urea-N (a sign of protein being broken down), meaning they’re preserving their muscle and tissues better.

37
0
84%

When people with low growth hormone take their hormone while fasting, their bodies burn more fat for energy instead of breaking down muscle.

37
0
78%

When people with low growth hormone take their hormone while fasting, their blood sugar goes up a little, but their body doesn’t use more or less glucose overall—so it’s just keeping sugar available without changing how it’s burned.

37
0
77%

When people with low growth hormone fast and take their hormone, their bodies produce less urea (a waste product from breaking down protein), meaning they’re not losing as much protein.

37
0
76%