When PGC-1α is increased in muscle cells, they break down a specific type of fat (lignoceric acid) more efficiently using both peroxisomes and mitochondria. This finding is from the abstract summary...

Pro

Against

Evidence from Studies

Supporting (1)

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Overexpression of PGC-1α increases peroxisomal activity and mitochondrial fatty acid oxidation in human primary myotubes.

Cross-Sectional Study

Human & In Vitro

2017 Apr 1

Contradicting (0)

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No contradicting evidence found

Source Study

Overexpression of PGC-1α increases peroxisomal activity and mitochondrial fatty acid oxidation in human primary myotubes.

Score: 33

DOI: 10.1152/ajpendo.00331.2016

Similar Assertions

Increasing PGC-1α in muscle cells leads to higher levels of mRNA for breaking down fats in peroxisomes. This finding is from the abstract summary - full study details were not available

85%

When muscle cells in a lab have more PGC-1α protein, they show higher levels of PMP70, which is a protein involved in peroxisome function. This finding is from the abstract summary - full study details were not available

72%