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v1
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Back to Study: Insights into the Underlying Mechanism of Ochratox...
mechanistic
Analysis v1
Strong Support

When this mold eats certain sugars like sucrose, glucose, or arabinose, it turns on genes that help make a toxin, and two of those genes become over three times more active than when it's eating something else.

6
Pro
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Against

Evidence from Studies

Supporting (1)

6

Community contributions welcome

6

Insights into the Underlying Mechanism of Ochratoxin A Production in Aspergillus niger CBS 513.88 Using Different Carbon Sources

Cross-Sectional Study
In Vitro
2022 Aug 12

The study shows that when this mold is grown on sugar, glucose, or arabinose instead of peptone, it turns on genes that make a harmful toxin, which matches what the claim says.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Insights into the Underlying Mechanism of Ochratoxin A Production in Aspergillus niger CBS 513.88 Using Different Carbon Sources

Score: 6
DOI: 10.3390/toxins14080551

Similar Assertions

In a certain mold used in industry, sugar sources like sucrose, glucose, and especially arabinose make it produce a toxin called ochratoxin A, but a protein-based nutrient called peptone stops the toxin from being made at all.

6
0
80%

In a type of mold called Aspergillus niger, turning off a specific gene (AnGal4) makes it produce a lot more of a toxin called ochratoxin A—especially when it's fed arabinose sugar.

6
0
76%

Some mold found in Brazilian food has the genes to make a harmful toxin called ochratoxin — about 1 in 30 of these molds could make it, but not another toxin, suggesting a small risky group we should watch.

5
0
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When this type of fungus grows on sugars like sucrose or glucose, its natural defenses (which help it handle stress) get weaker compared to when it grows on a protein-based food like peptone.

6
0
71%

When scientists turned off a specific gene called AnAzf1 in a mold called Aspergillus niger, it stopped making a toxin called ochratoxin A in lab tests.

4
0
71%