In a certain mold used in industry, sugar sources like sucrose, glucose, and especially arabinose make it produce a toxin called ochratoxin A, but a protein-based nutrient called peptone stops the toxin from being made at all.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Insights into the Underlying Mechanism of Ochratoxin A Production in Aspergillus niger CBS 513.88 Using Different Carbon Sources

Cross-Sectional Study

In Vitro

2022 Aug 12

The study shows that sugar sources like sucrose, glucose, and arabinose cause the fungus to make a toxin, while peptone stops it. This matches the main idea of the claim.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Insights into the Underlying Mechanism of Ochratoxin A Production in Aspergillus niger CBS 513.88 Using Different Carbon Sources

Score: 6

DOI: 10.3390/toxins14080551

Similar Assertions

When this mold eats certain sugars like sucrose, glucose, or arabinose, it turns on genes that help make a toxin, and two of those genes become over three times more active than when it's eating something else.

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80%

In a type of mold called Aspergillus niger, turning off a specific gene (AnGal4) makes it produce a lot more of a toxin called ochratoxin A—especially when it's fed arabinose sugar.

6

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78%

When scientists turned off a specific gene called AnAzf1 in a mold called Aspergillus niger, it stopped making a toxin called ochratoxin A in lab tests.

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75%