When tumors are acidic, certain healthy fats (n-3 and n-6) can kill cancer cells by causing a specific type of cell death called ferroptosis, especially if you block a storage mechanism in the cells.

Pro

Against

Evidence from Studies

Supporting (1)

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Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects.

Cohort Study

Animal

2021 Aug 3

Contradicting (0)

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No contradicting evidence found

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Source Study

Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects.

Score: 8

DOI: 10.1016/j.cmet.2021.05.016

Similar Assertions

When you block cancer cells from storing these fats and/or push them into ferroptosis, the cancer-killing effect of n-3 and n-6 fats gets even stronger.

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