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Strong Support

When normal-weight women eat fructose instead of glucose, it seems to lower the daily swing in their hunger hormone levels by about a quarter, which might mess with their body's natural hunger rhythm.

59
Pro
0
Against

Evidence from Studies

Supporting (1)

59

Community contributions welcome

59

Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women.

Randomized Controlled Trial
Human
2004 Jun

The study shows that when women drink fructose instead of glucose with meals, their leptin levels don’t go up and down as much during the day, which matches the claim.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

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Source Study

Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women.

Score: 59
DOI: 10.1210/JC.2003-031855

Similar Assertions

Drinking sugary drinks with fructose — even when not overweight — might lower a key fullness hormone in women more than drinking the same amount of glucose, which could mess with the brain’s ability to feel full.

59
0
83%

For normal-weight women, eating meals sweetened with fructose instead of glucose might make their bodies send weaker 'fullness' signals to the brain, because a key hormone called leptin drops by a third in the first 12 hours after eating.

59
0
76%

Eating early in the day lowers two key hormones (leptin and GLP-1) in the morning, which may reflect the body’s natural rhythm adjusting to food timing.

0
65
76%

In normal-weight women, eating fructose instead of the same amount of glucose might make them feel less full and more likely to eat more, because it changes key hunger and fullness hormones in the body.

59
0
73%