The Claim
In healthy adult humans, the coinfusion of GLP-1 at 1.2 pmol/kg/min and insulin at 1 mU/kg/min does not produce an additive effect on skeletal or cardiac muscle microvascular blood volume or blood flow compared to the administration of either hormone alone, suggesting that the microvascular actions of GLP-1 and insulin are not synergistic under physiological conditions.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When healthy adults get both GLP-1 and insulin at the same time, it doesn’t boost blood flow to their heart or muscles any more than using just one of the hormones alone.
See the scientific wording
In healthy adults, coinfusion of GLP-1 (1.2 pmol/kg/min) and insulin (1 mU/kg/min) does not further increase skeletal or cardiac muscle microvascular blood volume or blood flow beyond the individual effects of either hormone alone, indicating that their microvascular actions are not additive under physiological conditions.
What the research says
1 studyThe study found that giving both GLP-1 and insulin together doesn’t increase blood flow or volume in muscles more than either one alone — just like the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.