The Claim
In young, healthy males, the co-ingestion of 5 g creatine with a mixture of 14 g protein hydrolysate, 7 g leucine, 7 g phenylalanine, and 57 g dextrose stimulates insulin release to a similar extent as 5 g creatine with 95 g dextrose, and both combinations reduce urinary creatine excretion compared to creatine ingested with water alone.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
If young, healthy guys take creatine with a mix of sugar, protein bits, and certain amino acids, it triggers about as much insulin as taking creatine with just a lot of sugar — and both help the body hold onto more creatine than if they took it with water.
See the scientific wording
In young, healthy males, co-ingestion of 5 g creatine with 14 g protein hydrolysate, 7 g leucine, 7 g phenylalanine, and 57 g dextrose stimulates insulin release to a similar extent as 5 g creatine with 95 g dextrose, and both combinations reduce urinary creatine excretion compared to creatine with water alone.
What the research says
1 studyStudy: Optimization of insulin-mediated creatine retention during creatine feeding in humans
The study found that mixing creatine with a blend of protein, amino acids, and sugar boosted insulin and kept more creatine in the body just as well as mixing it with a lot of sugar alone.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.