The Claim
In young, resistance-trained men, prolonged muscle time under tension during low-load resistance exercise (6s/6s cadence) increases phosphorylation of p70S6K at 24 hours post-exercise, and this phosphorylation is correlated with delayed myofibrillar protein synthesis (r=0.42, P=0.02), indicating that p70S6K signaling mediates the delayed anabolic response.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In young men trained in resistance exercise, performing low-load lifts with a slow 6-second contraction and 6-second relaxation increases phosphorylation of the p70S6K protein at 24 hours after exercise, and this increase is statistically associated with a delay in the rate of myofibrillar protein synthesis.
See the scientific wording
In young, resistance-trained men, prolonged muscle time under tension during low-load resistance exercise (6s/6s cadence) increases phosphorylation of p70S6K at 24 hours post-exercise, which correlates with delayed myofibrillar protein synthesis (r=0.42, P=0.02), suggesting p70S6K signaling mediates the delayed anabolic response.
When muscles are worked slowly under light weight until tired, the prolonged strain recruits all muscle fibers and creates lasting chemical signals inside the cells. These signals keep the growth pathway active for hours, and when protein is eaten later, the muscle uses it to build more contractile proteins, leading to growth that starts 24 hours after exercise.
What the research says
1 studyWhen young men lift light weights slowly until tired, their muscles make more protein 24 hours later—and a key signaling molecule called p70S6K becomes more active at the same time, suggesting it helps trigger muscle growth after slow lifting.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
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