The Claim
In female rats consuming 13% (w/v) HFCS-55 for 8 weeks, hepatic export of triglycerides via lipoprotein secretion is not increased, whereas consumption of sucrose is associated with up-regulation of microsomal triglyceride transfer protein, indicating that HFCS-55 impairs the liver’s ability to clear excess fat.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Female rats fed a diet with 13% HFCS-55 for 8 weeks showed no increase in the liver's export of triglycerides, while rats fed sucrose showed increased activity of a protein involved in fat transport, indicating HFCS-55 reduces the liver's capacity to remove excess fat.
See the scientific wording
In female rats consuming 13% (w/v) HFCS-55 for 8 weeks, hepatic export of triglycerides via lipoprotein secretion was not increased, unlike in rats consuming sucrose, which showed up-regulation of microsomal triglyceride transfer protein, suggesting HFCS-55 impairs the liver’s ability to clear excess fat.
When fructose from HFCS-55 enters the liver, it triggers the production of new fat molecules and blocks the breakdown of existing fat. At the same time, it prevents the liver from packaging fat into particles that can be shipped out to other tissues. This causes fat to build up inside liver cells.
What the research says
1 studyRats that drank HFCS-55 couldn’t get fat out of their liver as well as rats that drank sugar water, so their livers got greasier. The sugar in HFCS-55 seems to block the liver’s fat-export system.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.