Over an 8-week training program targeting the elbow flexors, untrained females performed more total resistance exercise volume than untrained males, but both groups showed similar increases in muscle...
Mechanism
Synthesis from 1 study
Women lifted more overall, but their muscles didn’t grow bigger or stronger than men’s because each lift triggered the same muscle-building response. Doing more lifts didn’t add extra growth — it just repeated the same signal over and over.
Most probable mechanism
Even though women did more total exercise, their muscles didn’t grow bigger or stronger than men’s because each lift they did triggered the same muscle-building signals as each lift men did — so more lifts didn’t mean more growth, just more of the same signal.
Females perform a greater total mechanical load during resistance training due to higher repetition counts or work volume.
Mechanical tension from each repetition activates mTORC1 signaling pathways in muscle fibers at a similar rate per unit of load between sexes.
Protein synthesis rates and satellite cell activity increase proportionally to mechanical load, not total volume, resulting in comparable net muscle growth despite differing total work.
Evidence from Studies
Supporting (1)
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Contradicting (0)
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