Women who work nights might have lower levels of the 'good' cholesterol than women who work during the day, but this doesn’t seem to happen in men—so night shifts might affect women’s cholesterol differently.

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Evidence from Studies

Supporting (0)

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No supporting evidence found

Contradicting (1)

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Association between night shift work and markers of metabolism, cardiovascular and immune system in a population-based German cohort

Cross-Sectional Study

Human

2025 Jun

The study looked at whether working nights affects cholesterol levels, and while it noticed a tiny hint that women might be different, it couldn’t confirm it — so we can’t say for sure that night shifts lower women’s good cholesterol.

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Association between night shift work and markers of metabolism, cardiovascular and immune system in a population-based German cohort

Score: 61

DOI: 10.1007/s11357-025-01596-8

Similar Assertions

Working nights might affect your health differently depending on things like your gender, when you naturally feel awake or sleepy, or how much money you make — but this study didn’t check any of those things, so we can’t fully explain why other studies have found different results.

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