descriptive
Analysis v1
Strong Support
Women with systemic sclerosis produce more cortisol over the course of a day than healthy women, even though their immediate cortisol response to stress is similar. This suggests a difference in overall cortisol regulation that is not tied to short-term stress reactions.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
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Does stress response axis activation differ between patients with autoimmune disease and healthy people?
Cross-Sectional Study
Human
2024 AugWomen with systemic sclerosis make more cortisol throughout the day than healthy women, even though their bodies react the same way when they’re stressed — meaning their stress system is overactive all the time, not just during stressful moments.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.