Young men who drank β-lactoglobulin had higher levels of branched-chain and essential amino acids in their blood over time compared to those who drank regular whey protein.
Scientific Claim
In 10 young healthy males, β-lactoglobulin supplementation led to significantly higher plasma branched-chain amino acid (35,132 vs. 28,654 μM·min, p=0.001) and essential amino acid (40,321 vs. 35,210 μM·min, p=0.023) area under the curve compared to whey protein isolate.
Original Statement
“In terms of AUC analyses, LEU AUC was significantly different between the WPI and BLG groups (14,762 ± 2785 μM·min vs. 19,954 ± 2970 μM·min, p = 0.007). Similarly, BCAA AUC was significantly different between WPI and BLG groups (28,654 ± 6970 μM·min vs. 35,132 ± 4962 μM·min, p = 0.001). EAA AUC was also significantly different between WPI and BLG groups (35,210 ± 8142 μM·min vs. 40,321 ± 6275 μM·min, p = 0.023) with BLG showing superior aminoacidaemia across the spectrum of EAA clusters.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
The RCT design with precise AUC measurements allows definitive claims about amino acid concentration differences.
Evidence from Studies
Supporting (1)
The Effect of Leucine-Enriched β-Lactoglobulin Versus an Isonitrogenous Whey Protein Isolate on Skeletal Muscle Protein Anabolism in Young Healthy Males