When baby zebrafish have higher stress hormone levels early in life, it seems to change how certain genes in their brain work—turning down one gene linked to stress control and turning up another—hinting at how early stress might rewire their stress response system.

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Evidence from Studies

Supporting (1)

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Optogenetic induction of chronic glucocorticoid exposure in early‐life leads to blunted stress‐response in larval zebrafish

Cross-Sectional Study

Animal

2024 Jun

The study shows that raising stress hormone levels early in zebrafish larvae leads to changes in brain genes linked to stress control, which is exactly what the claim says happens.

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Source Study

Optogenetic induction of chronic glucocorticoid exposure in early‐life leads to blunted stress‐response in larval zebrafish

Score: 6

DOI: 10.1111/ejn.16301

Similar Assertions

If baby zebrafish have too much of a stress hormone early in life, they might not react as strongly to stress later on — like their stress system gets 'numb' and stays that way.

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