The Claim

Parasympathetic nervous system activity, as indexed by high-frequency heart rate variability, is associated with reciprocal regulation of pro-inflammatory (NF-κB) and antiviral (IRF) gene pathways in human immune cells, supporting the hypothesis that autonomic balance modulates innate immune function.

Source: Parasympathetic neural activity and the reciprocal regulation of innate antiviral and inflammatory genes in the human immune system

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
44score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

When your body is calm and relaxed, your nervous system might help balance your immune system’s fight against inflammation and viruses — like a natural thermostat for your body’s defenses.

See the scientific wording

The reciprocal regulation of pro-inflammatory (NF-κB) and antiviral (IRF) gene pathways in human immune cells is associated with parasympathetic nervous system activity, as indexed by high-frequency heart rate variability, supporting the hypothesis that autonomic balance modulates innate immune function.

What the research says

1 study
  1. Study: Parasympathetic neural activity and the reciprocal regulation of innate antiviral and inflammatory genes in the human immune system

    When your body is calm and your heart rate variability is high, your immune system turns down inflammation and turns up antiviral defenses — like switching from 'fighting bugs' to 'preventing viruses'.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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