The Claim
Acute stimulation of muscle protein synthesis saturates at a dose of approximately 0.25 g/kg of high-quality protein, and ingestion of protein beyond this dose results in increased amino acid oxidation without further elevation of muscle protein synthesis.
What the research says
Not yet evaluated
We are still looking at what the research says.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Consuming more than 0.25 grams of high-quality protein per kilogram of body weight in a single meal does not increase muscle protein synthesis beyond that point; excess protein is instead broken down for energy.
See the scientific wording
The acute stimulation of muscle protein synthesis saturates after consuming approximately 0.25 g/kg of high-quality protein, and additional protein beyond this dose does not further increase synthesis, leading to increased amino acid oxidation instead.
When you eat protein, your body breaks it down into amino acids that signal muscles to build new proteins. This signal peaks at a certain amount of protein and then shuts off, even if more amino acids are still in the blood. Any extra amino acids that can't be used for building muscle get broken down for energy instead.
What the research says
1 studyYour muscles can only use about 0.25 grams of protein per kilogram of body weight at once to build new tissue. Eating more than that in one meal doesn’t help build more muscle — the extra just gets used for energy instead.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.